No Match for David Spade

3/21/2008 7:00 PM PDT BY TMZ STAFF
Fran Drescher got the pap shaft last night. TMZ's photog literally ran from The Nanny to A-list celeb David Spade.

The cameraman then had the audacity to return to Fran, who talked about her "genes." Notice the cameraman zooming out to look at her jeans ... which she wasn't wearing.