George Clooney and Elisabetta -- IT'S OVER!!!!

6/22/2011 8:25 AM PDT BY TMZ STAFF
It was only a matter of time ... but professional playboy George Clooney is finally moving on from his super-hot Italian GF of two years Elisabetta Canalis ... and her UNBELIEVABLE physique.

George Clooney

The former couple just released a joint statement -- "We are not together anymore. It's very difficult and very personal, and we hope everyone can respect our privacy."

Who's next????