EXCLUSIVE

Twist was with Bieber in a Newport Beach hotel room last week, where, we're told, the rapper was happily rolling blunts for J.B. and others.
Sources familiar with the situation tell TMZ ... JB and Twist have become tight ... and have been smoking together on a number of other occasions.

Twist's Twitter profile pic makes it clear ... he's a fan.
Sources involved in Justin's life who care about him are deeply concerned that Twist has become a powerful negative influence in his life and feel very strongly Justin needs a clean break from the rapper or else bad things are going to happen.

FYI ... Lil Twist is signed by Lil Wayne and close knit with the Cash Money and Young Money crews.