Tatted Up 49ers Star Colin Kaepernick -- Ink Biz BOOMING for QB's Tattoo Artist

Colin Kaepernick's meteoric rise hasn't just been great for the 49ers ... it's also been HUGE for his longtime tattoo artist ... who tells TMZ business has exploded ever since the inked up QB led SF into the playoffs.

We spoke with tat artist Nes Andrion -- who's been working on Colin for years at his shop in Reno where CK played his college ball.

Andrion tells us ... ever since Colin started winning games in November -- when starting QB Alex Smith got a concussion -- customers have been pouring in, asking for 49ers-themed ink.

Nes tells us, "People come in and ask if I am the artist that does Colin’s tattoos, and ask when I think I am going to tattoo him again.”

Nes adds, “People want to get their tattoos done by the same artist as Colin Kaepernick."

According to Nes, Colin will be coming back in the off-season to finish his enormous angel-demon-themed chest piece.

It's pretty hilarious though, considering Nes is a proud Patriots fan -- but now that Colin's winning, he secretly hopes the 49ers can bring home the Lombardi trophy this year.

"To be honest I want [Colin] to take it even though the Pats are my team. He puts money in my pocket."