Lamar Odom was drunk -- very drunk -- at Beacher's Madhouse in Hollywood Wednesday night ... eyewitnesses tell TMZ -- and it's a dramatic, depressing turn in his life.
People who were present tell us ... Lamar showed up with several guys. In short order Lamar was hanging at the bar doing shots of Patron. For the next 3 hours, Lamar could not be seen without a glass of champagne.
Our sources say he was "hammered." One witness -- who knows the difference -- says Lamar didn't seem like he was on drugs. It appeared to be alcohol-fueled.
Lamar stayed until closing at 2 AM. By 2:30 AM he was in the valet area talking about where to go for the "after party."
Lamar claims he's been clean for the last few weeks. Khloe Kardashian even invited him to a Kanye West concert earlier in the week as a show of support, although we're told she's already decided to divorce him.