Kanye West Goes Ballistic on Radio DJs -- SHUT THE F*** UP!!!!!!

Brace yourselves folks ... Kanye West went OFF on radio DJs last night during his concert -- telling them all to "SHUT THE F*** UP!!!!" -- and this rant might be his loudest yet ... comparing himself to Beethoven and Shakespeare.

Kanye -- who was performing in University Park, PA -- was responding to recent antagonistic radio interviews ... specifically by radio DJs Sway and Charlemagne Tha God, who called Kanye "egotistical" and "narcissistic" on the air.

Kanye responded ... "If I go to a radio interview, SHUT THE F*** UP!!! ... Diss me, talk sh*t. What the f*** did you do? What have you done with your motherf**kin' life, Charlemagne? Sway?"

Warning: turn down your speakers.