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Sean Penn: Flips Out On Fan, Slams Fan Cellphone

Sean Penn went nuclear on a fan in a fancy San Francisco hotel last night -- threatening to jack the guy up after Sean caught him trying to sneak a cell phone pic ... and TMZ has the explosive footage. Penn was at the Lobby Bar at the St. Regis Hotel in the Financial District ... when he saw a flash go off from another patron's cell phone and realized the guy was trying to take a photo.

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