Selma Blair: I Blacked Out On Booze and Meds

Selma Blair is apologizing for her outburst on her flight back from Cancun, and admitting she mixed alcohol with pills.

Blair says, "I made a big mistake yesterday. After a lovely trip with my son and his Dad, I mixed alcohol with medication, and that caused me to black out and led me to say and do things that I deeply regret."

TMZ broke the story ... Selma yelled, "He burns my private parts" and "He beats me. He's going to kill me" -- before being removed by stretcher and taken to a hospital.

In her statement to Vanity Fair she added, "I take this very seriously, and I apologize to all of the passengers and crew that I disturbed and am thankful to all of the people who helped me in the aftermath. I am a flawed human being who makes mistakes and am filled with shame over this incident. I am truly very sorry.”

She says the only saving grace was that her son was asleep with headphones on during the incident.