Rosanna Arquette -- Good Genes or Good Docs?

2/13/2011 9:00 AM PST

Rosanna Arquette -- Good Genes or Good Docs?

Rosanna Arquette knows good work when she sees it.


Here's the 26-year-old actress/director/producer back in 1986 (left) -- and 25 years later, the 51-year-old version at an event in L.A. this week (right).

Desperately seeking ... her secret.