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Christina Applegate says she's been hospitalized "upwards of 30 times" from throwing up, diarrhea, and excruciating pain ... and she thinks it stems from her MS.

The "Married... with Children" star -- who was diagnosed with multiple sclerosis in 2021 -- opened up about her rather crappy experiences on her latest 'MeSsy' podcast episode as she and her cohost Jamie-Lynn Sigler addressed a note from a listener also battling the autoimmune disease and dealing with frequent diarrhea and vomiting.

During the candid discussion, CA admits when she needs to go No. 2, she oftentimes also pukes ... and is certain there's a correlation between her upset stomach and MS, despite doctors not being totally convinced.

Jack Schlossberg — the grandson of John F. Kennedy — went ballistic on social media for not getting a heads up on the release of the late president's 1963 assassination files by the Trump administration.

Schlossberg jumped on X Tuesday and blasted the Trump administration for failing to notify anyone in the Kennedy clan — except Robert F. Kennedy Jr. — about the massive JFK document dump, totaling 80,000 pages!

Schlossberg said it all came as a "total surprise," but Trump's actions were not a shock, noting that RFK Jr. "definitely knew." (RFK Jr. serves as Trump's Secretary of Health and Human Services.)

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Getting to the gym can be a chore so motivate yourself with a cute new workout set!

Whether you’re looking for biker shorts and a crop top or leggings that’ll snatch your waist, we’ve got all the sets that’ll have you making a statement while you’re breaking a sweat.

Because when you look good, you feel good -- and nothing can boost your confidence like a good gym ’fit!

You’ll be looking pretty in pink in this Long Sleeve Crop Top & Biker Shorts Set!

Steven Spielberg’s daughter had a front-row seat to an unforgettable moment at her first-ever courtside NBA game Monday night—sitting next to Tracy Morgan as he threw up all over the court at the New York Knicks game.

Destry Allyn Spielberg took to Instagram on Tuesday to make light of the awkward moment ... sharing a hilarious photo of herself looking absolutely disgusted as she sat one seat away from the 'SNL' star while he got sick.

She jokes that she "had a great time" in her first meme-worthy photo, then followed up with a snap of Tracy spewing vomit, overlaid with a shrugging emoji. Hey, s*** happens!

If Jonathan Majors ever gets tired of being an A-list actor, weightlifting legend Ronnie Coleman tells TMZ Sports the dude could seriously be a pro bodybuilder!!

Coleman made the proclamation in a sit-down with us on Tuesday -- just a few days after he had put Majors through a grueling chest and arms workout in Colombia.

Coleman said he was so impressed with Majors' muscles during the gym session, he came away certain that if he coached Majors for around 6-to-12 months, the 35-year-old would be able to compete for hardware at real-deal physique shows.

The person of interest in the case of missing University of Pittsburgh student Sudiksha Konanki is free to leave the Dominican Republic and return home.

A judge ruled Tuesday that Joshua Riibe, the last person to see Konanki alive, has the green light to go back to the United States.

The decision came down after an hours long court hearing which saw Riibe tell the judge, "I really want to be able to go home, talk to my family, give them hugs, tell them I miss them" ... according to Noticias SIN -- a TV news station in the DR.

Talk about havin' a blast on the beach ... A-lister Gabrielle Union may be in her 50s, but these scorchin' shots she shared on Instagram say otherwise 🔥!

The mom with the rockin' bod was livin' it up in Miami and posted a few enticing photos which lured in 21+ million followers ... Needless to say, Dwyane Wade is one lucky man!

Jonathan Majors and Meagan Good are married ... according to a report.

The couple got hitched Tuesday in a small, private wedding at their Los Angeles home ... ET reported, citing sources.

Jonathan and Meagan's wedding comes just days before he's set to return to the big screen with his new movie out Friday, "Magazine Dreams."

American actor Hawthorne James was 43 years old when he played Sam -- the Los Angeles bus driver who is shot after he and his passengers discover a planted bomb -- in the action/thriller film "Speed" back in 1994.

James was joined by Hollywood icons like Keanu Reeves as the fearless and daring LAPD officer going after the bomber, Jack, Sandra Bullock as the broke Los Angeles passenger who steps up and drives the bus to safety, Annie, and Dennis Hopper as the former police officer and bomber seeking revenge on the LAPD, Howard.

A college baseball player allegedly ambushed an elderly man in a California bar, knocking the HELL out of him during a drunken altercation that was all caught on video.

Law enforcement sources tell TMZ ... Owen Hayes, 21, allegedly got into a heated confrontation with an 84-year-old man inside a Santa Clarita dive bar -- and the tensions soon turned violent.

Check out video, obtained by TMZ, which shows the fight that took place in the early morning hours of February 28. It starts with one guy arguing with the geriatric customer, as another man eventually steps between them.

Then the video cuts to a different man -- allegedly Hayes -- rushing up behind the victim and knocking him to the floor. The older gentleman was reportedly knocked unconscious and hospitalized but fortunately not seriously injured

An employee for the bar tells us the victim is a regular at the Doc’s Inn and said the incident was an unprovoked assault.

Teyana Taylor's legal team wants her ex-husband Iman Shumpert locked up for contempt ... claiming he deliberately leaked sealed documents about their divorce to the media!!!

According to docs, obtained by TMZ Hip Hop, Teyana claims she's been getting skewered on social media over misleading reports about who got what in their divorce.

Taylor insists it wasn't a "settlement" at all because the parties only got what was awarded by the court ... including vehicles and a tour bus, which she says she paid for on her own.

After 286 days in space, two American astronauts who've been stuck on the International Space Station since last spring are finally back down on Earth.

Butch Wilmore and Sunita "Suni" Williams splashed down softly off the coast of Tallahassee, Florida today at about 5:58 PM ET, following a 19-hour journey in a SpaceX spacecraft, alongside astronauts Nick Hague and Aleksandr Gorbunov.

It was a smooth arrival back to Planet Earth, with Dragon Freedom’s Crew-9 parachutes deploying 6,000 feet in the air, and the control room erupting in cheers as they splashed down into the water.

Donald Trump's push to revoke Hunter and Ashley Biden's Secret Service protection has found some support from an ex-Secret Service agent.

Richard Staropoli, a former special agent with 25 years in the Secret Service, joined us Tuesday to talk about backing Trump’s decision, arguing it’s an extremely costly measure and there’s no real threat justifying their need for protection.

Staropoli -- who was appointed by Trump as the Chief Information Officer for the Department of Homeland Security in 2017 -- broke down the details of Secret Service protection, explaining it’s funded by U.S. taxpayers -- and he dives deep into the costs of providing protection for Hunter and Ashley.

Anthony Davis isn't ready to get back on the NBA court just yet, but here's a good sign for Dallas Mavericks fans -- the Brow was able to hit the golf course and work on his game on Tuesday.

A clip of AD's round was shared to social media ... with the 6'10" baller -- who went down with a left adductor strain on Feb. 8 -- appearing to gear up for a chip shot.

Davis rocked shorts, a t-shirt and a vest for the occasion ... and it looked like he had a stogie in his mouth.

D.L. Hughley is all in on Don Lemon's take, saying he agrees -- you can be Black and Republican, but supporting MAGA? That's a no-go.

We caught up with D.L. on "TMZ Live" Tuesday and he didn’t hold back -- saying Black people know they'll be tokenized, especially since Trump’s just using Black voters, trotting them out when it suits him ... like when Stephen A. Smith claimed Black people relate to Trump because of his felony convictions.

Catch the video ... D.L. dives deeper into his examples, noting how the Prez uses marginalized groups to sanitize his stances.