Neil Patrick Harris GOOD GENES OR GOOD DOCS?

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Neil Patrick Harris' good looks are center stage!

Here's the then 16-year-old "Doogie Howser, M.D." doctor at a Los Angeles holiday party back in 1989 (left) and 25 years later -- the now 41-year-old Broadway badass leaving a New York City theater late last month (right).

What's up doc?

The question is...

Courtney Love GOOD GENES OR GOOD DOCS?

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Courtney Love's look is "mid-century."

Here's the then 31-year-old Kurt Cobain widow and "Hole" singer on stage in 1995 (left) and almost 20 years later -- the now 50-year-old mother of one at a theater in New York City earlier this year (right).

The question is...

JON BON JOVI GOOD GENES OR GOOD DOCS?

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Jon Bon Jovi's American looks are stuck in the '80s!

Here's a 24-year-old teased out version of the "Livin' On A Prayer" singer back in 1986 (left) and 28 years later -- the now 52-year-old father of four at a benefit in New York City earlier this year (right).

He's going down in a blaze of glory.

The question is...

JENNY MCCARTHY GOOD GENES OR GOOD DOCS?

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Jenny McCarthy's looks have never been let go.

Here's the then 23-year-old "Singled Out" host at the MTV Movie Awards in L.A. back in 1995 (left) and 19 years later -- the now 41-year-old "The View" outcast at an NYC party earlier this year (right).

What a view!

The question is...

HILLARY CLINTON GOOD GENES OR GOOD DOCS?

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Hillary Clinton's looks are a facial filibuster!

Here's the then 44-year-old soon-to-be First Lady posing for a photo in Los Angeles back in 1991 (left) and 23 years later -- the now 66-year-old former Secretary of State speaking at an event in New York City earlier this year (right).

Her beauty secrets are classified information!

The question is...

OLSEN TWINS GOOD GENES OR GOOD DOCS?

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Ashley and Mary-Kate Olsen's beauty is not going out of style.

Here's the famous "Full House" sisters at a fashion event in New York City shortly after celebrating their 18th birthday back in 2004 (top) and ten years later -- the now 28-year-old fraternal twinsies at another fashion event in New York City (bottom).

Two of a kind.

The question is...

JOHN WATERS: GOOD GENES OR GOOD DOCS?

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John Waters' looks are divine.

Here's the then 44-year-old film maker sporting his signature pencil-thin moustache at an east coast film premiere back in 1990 (left) and 24 years later, the now 68-year-old cult classic icon at his book release last week in NYC (right).

"Beauty is looks you can never forget."

The question is...

CHRIS ROCK GOOD GENES OR GOOD DOCS?

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Chris' good looks are as solid as a ROCK!

Here's a 26-year-old version of the SNL funny man at a Los Angeles theater back in 1991 (left) and 23 years later -- the now 49-year-old comedy god making an appearance on a TV show in New York City earlier this week (right).

His handsome face is nothing to laugh at.

The question is...

MARTHA STEWART GOOD GENES OR GOOD DOCS?

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Martha Stewart's beauty has never been locked up!

Here's a then 48-year-old version (complete with blue contacts) of the farm chic star at a Hollywood movie premiere back in 1989 (left) and 25 years later -- the now brown-eyed 72-year-old media mogul at a party in NYC earlier this year (right).

What's cookin' good lookin'?

The question is...

Jason Alexander GOOD GENES OR GOOD DOCS?

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There's nothing funny about Jason Alexander's looks!

Here's the the 35-year-old "Seinfeld" star at a comedy benefit back in 1994 (left) and 20 years later, the now 54-year-old father of two at a fancy ball in Beverley Hills earlier this week (right).

"I think it moved."

The question is...

Alicia Silverstone GOOD GENES OR GOOD DOCS?

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Alicia Silverstone is still a total betty!

Here's the 18-year-old version of the uber-cute "Clueless" star at a premiere in Los Angeles back in 1994 (left) -- and 20 years later, the now 37-year-old mother and author at a book signing in New York earlier this month (right).

Like, the question is...

BOB SAGET GOOD GENES OR GOOD DOCS?

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Bob Saget's looks are nothing to laugh at!

Here's the then 38-year-old "Full House" patriarch at a hockey game in Los Angeles back in 1994 (left) and 20 years later, the foul mouthed 57-year-old father of three at a book event in New York City earlier this month (right).

"Whatever happened to predictability?"

The question is...

Leslie Mann GOOD GENES OR GOOD DOCS?

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Leslie Mann she looks good!

Here's the then 24-year-old "Cable Guy" babe at a premiere in Los Angeles back in 1996 (left) and 18 years later, the now 42-year-old mother of two at a movie conference in Las Vegas earlier this year (right).

"This is 20?"

The question is...

JULIE BOWEN GOOD GENES OR GOOD DOCS?

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Julie Bowen's beauty is a modern miracle!

Here's the then 26-year-old babe in the golf comedy "Happy Gilmore" back in 1996 (left) -- and 18 years later, the 43-year-old "Modern Family" mom earlier in the year in Sydney, Australia (right).

The question is...

Salma Hayek GOOD GENES OR GOOD DOCS?

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Salma Hayek has always kept a lid on her incredibly good looks.

Here's the then 32-year-old "Dogma" actress showing off in a lilac "Blossom" inspired bucket hat at an LA premiere in 1998 (left) and 16 years later -- the now 47-year-old "30 Rock" star looking tough in a black biker cap at a fashion show in Milan earlier this month (right).

Our hats off to her.

The question is...

Elle Macpherson GOOD GENES OR GOOD DOCS?

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Elle Macpherson is a model of genetic superiority.

Here's the then 25-year-old Sports Illustrated cover girl at a New York City event back in 1989 (left) and 25 years later -- the now 49-year-old mother of two at a fashion event in Paris earlier this year (right).

Elle-oh!

The question is...