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Oprah & Gayle -- Targeted in Lesbian Sex Tape

12/10/2010 8:10 PM PST BY TMZ STAFF

Oprah Winfrey may not be a lesbian -- but the chick who's gonna play the talk show host in a brand new sex tape sure is.

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Just as soon as the real Oprah wiped away her tears of endearment for her bestest non-lesbianic gal pal Gayle King during a Barbara Walters interview this week ... Hustler had already locked down a couple of O and G not-really-lookalikes for an XXX re-imagining of their friendship.

FYI -- the chick on the left (Misty Stone) is playing Oprah ... and the one on the right (Bella Moretti) is Gayle.

The XXX flick -- entitled "Untrue Hollywood Stories: Oprah" -- is being released in January -- which sucks ... because it would have made one hell of a stocking stuff her.

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