Sheen took the stage around 8:37 PM ET to a semi-standing ovation. The crowd was mostly on his side ... but booed him when he said he quit drugs. Security tossed out a few hecklers early on.
Charlie invited "Two and a Half Men" creator Chuck Lorre to join him on stage at Radio City for Sunday night's show to "work this s**t out. Of course I want my job back man!"
Our sources connected to "Men" tell us producers will never let Sheen back on the show. Sorry, Charlie.
Sheen told barely coherent stories about the different hotels he stayed in, his incident at the plaza, locking himself in an airplane bathroom with a seven-gram cocaine rock, and how he once performed CPR on a model in a heroin coma. Who hasn't?
But by the end, Charlie had lost the crowd. The show ended abruptly -- roughly 30 minutes shorter than Sheen's shows in Ohio -- to a mix of boos and cheers ... but the boos carried the night.
Charlie's closer -- "I love you New York ... you're the best crowd ever. Well, some of you."
On his way out, Charlie was met by several fans and autograph seekers, but he seemed focused on just getting out of there.