'Biggest Loser' -- Dr. H's Wife Files for Separation

The wife of Dr. H from "Biggest Loser" is dropping some serious weight -- as in her own husband -- she's filing for legal separation after almost 33 YEARS of marriage.

Wanda Huizenga filed the papers in L.A. County Superior Court against the good doc -- real name Robert Huizenga -- citing "irreconcilable differences."

The couple was married in August 1979 and split in May this year. They have no minor children.