Scott Disick Parties in Vegas, Kourtney Home Alone (VIDEO)

Scott Disick is in full-on single mode, partying in Vegas and making lots of bank at the same time.

Scott raked in $50K for his appearance Friday night at 1Oak at the Mirage in Vegas. He was heavily guarded ... the only ones able to penetrate security were pretty girls.

Scott left alone but his party pal Mally Mall breezed out in a party bus with 40 of his closest friends ... all extremely female.

Meanwhile, back at the ranch, Kourtney Kardashian Instagrammed this pic of her watching Scooby- Doo with her kid.

Different ways to spend Friday night.