Jose Canseco's Wife Leila Knight -- We're Trying to Have Twins ... But He's Got Issues (VIDEO)

Jose Canseco's gonna be a daddy again -- if he can just sort out some fertility issues that might be tied to his past steroid use ... according to his wife, Leila Knight.

Leila was leaving Katsuya in Hollywood and decided to break the news -- she and Jose are trying to get knocked up ... with TWINS! Leila says they're going through in vitro right now, and they're even removing those pesky 'Y' chromosomes to ensure they get girls, 'cause she doesn't want carbon copies of Jose and his twin bro. Her words, not ours.

But she admits there's some stuff Jose has "to get off of and get on" before they get the job done. And don't miss her jab at Jose's age at the end!