Call of Duty -- Creator's Wife Files for Mega-Divorce

Call of Duty creator Vincent Zampella apparently has his own conflicts ... his wife just filed for divorce.

Brigitte Zampella cites irreconcilable differences as the reason she's ending their 18 year marriage, and the stakes are high. The wildly successful video game, launched in 2003, has grossed $11 BILLION in retail sales.

Vincent sued Activision in 2010 over ownership rights to the game and the case settled 2 years later. We're told Activision owns the game but Vincent got a whopping payout.

There's no evidence of a prenup -- nothing in the divorce docs -- which means under California law assets acquired during the marriage are split 50/50.

The couple has 3 minor children, and Brigitte wants primary physical custody.

Brigitte is asking for spousal support.

Our sources say the divorce is friendly ... not a real-life war game.