Oprah Winfrey followed that old adage ... when in Rome, shop your freaking face off and flaunt your overpriced purchases to the peasants.
The Big O hit up Via Condotti (Rome's way snootier version of Rodeo Drive) with her entourage -- including BFF Gayle King ... and proceeded to drop major Euros in Ermanno Scervino.
Oprah walked out loaded down with 4 huge bags from the high fashion store. Gayle had 1 ... but it's all relative, right?
Somewhere an Italian salesperson is celebrating tonight.
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