Nothing could stop Celine Dion as she belted out her hits for the final show of an amazing 16-year run on the Vegas Strip -- nothing except some guy with a small bladder.
Celine performed her 1,144th show Saturday night at the Colosseum at Caesars Palace ... where the crowd caught all the feels -- but at one point she delayed the show for one special fan's bathroom break.
She noticed him getting up, and waited until he returned to his front-row seat to restart the show. Celine joked it was the least she could do, considering he was probably broke after dropping big money on 2 tickets to the big Vegas finale. She also practiced good hygiene ... watch the clip.