Madonna had some words for Andy Cohen ... playfully airing her grievances with him after spotting him at her "Celebration" tour in NYC.
The Queen of Pop advised the talk show host to steer clear of any future digs on "Watch What Happens Live" ... with a clip showing her walking up to him with a bottle in hand during Saturday's show, asking, "How f****** lucky am I, Andy?"
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"If you say one more bad thing about me on your show," she began jolting her drink forward enough for some spillage near Andy -- cautioning: "Oh yeah, you're gonna be in so much trouble. You little troublemaking queen!!"
A public talking to from Madonna would make many want to dissipate into a deep, dark hole -- but Andy was delighted by the scolding -- mouthing "I love you" to the star.