Type 2 diabetic Paula Deen is unfazed by her life-threatening disease -- practically unhinging her jaw this week on a Caribbean cruise ... to take a heart-stopping bite out of a cheeseburger.

The picture was snapped Monday on board a Celebrity cruise ship -- where the 65-year-old is currently tempting fate, hosting her annual "Party-at-Sea" vacation for 400 devoted followers. It's hard to see, but there are also fries on her plate.

The cruise left Miami on Saturday -- and it's set to visit Puerto Rico, St. Thomas, and St. Maarten on the 7-day calorie-filled round trip.

So far, it's unclear if they serve salads.