Rob Lowe is getting ready to re-try Casey Anthony ... in an upcoming movie about the infamous murder case ... and the actor tells TMZ he's VERY confident people are "gonna dig it."
Lowe was in Malibu yesterday when we asked about "Prosecuting Casey Anthony" -- a Lifetime flick in which Rob is set to play Jeff Ashton, the man who prosecuted Tot Mom for the alleged murder of her daughter Caylee Anthony.
Rob tells TMZ, "It's gonna be interesting ... I think people are gonna dig it ... great script."
Lowe says production starts Monday ... and he's hoping the project will air sometime in January .... roughly 4-and-a-half years after Caylee was murdered.