'Biggest Loser' -- The Show Must Go On ... WITHOUT THE QUITTERS!!!

The "Biggest Loser" has trimmed some serious fat ... TMZ has learned TWO of the contestants who walked off the set this week have been cut loose for good ... and the show will continue without them.

TMZ has obtained photos taken today at the "Loser" ranch ... where production has resumed following a mass mutiny this week. TMZ broke the story ... several competitors stormed off the show in protest after getting word about a possible game "twist" that would give previously eliminated losers a shot at the $250k prize.

Sources connected to the show tell us ... producers are considering using the mutiny as a story point.