Anderson Cooper hates Barbie Mom ... HATES HER ... and made sure she knew it this week when he kicked her plastic ass off his talk show.
Cooper was trying his best to understand why the hell Sarah Burge -- aka the Human Barbie -- would want to Botox her 15-year-old daughter to get her to sweat less during beauty pageants.
When Burge started blathering on with some stupid explanation, Coop cut her off ... saying, "I gotta be honest, I gotta just stop. I'm sorry. I try to be really polite to all my guests, but I just think you're dreadful."
He added, "I honestly don't want to talk to you anymore."
Anderson later released a video statement saying, "I regret having her on in the first place and I regret that that's how things ended.