Tyga had a big birthday bash Thursday night, and someone was noticeably missing ... Kylie Jenner.
Tyga kicked things off at The Nice Guy in West Hollywood, where he and a bunch of pals grabbed dinner.
They took the party down the road to 1 OAK, where he celebrated his birthday with A$AP Rocky, Wiz Khalifa, Jamie Foxx, Leo DiCaprio and lots of others ... but no Jenners and no Kardashians.
In fact, Kylie didn't mention Tyga or wish him happy birthday on social medial at all, nor did any of her sisters.
Something interesting ... Kendall Jenner did post a pic giving the middle finger ... the question, to who?