Shawne Merriman: 1-Handed Shaquem Griffin Proved He's 'NFL Ready' at Combine

One-handed prospect Shaquem Griffin is "no doubt" making the NFL -- so says Shawne Merriman, who's convinced the talk of the combine is gonna overcome the odds and get drafted.

"He sure as hell looks NFL ready. He's a beast," Merriman told TMZ Sports.

FYI, the UCF stud ran the fastest 40 time for a linebacker in 15 YEARS over the weekend (4.38) ... and also put up 20 REPS with a prosthetic left hand.

Shawne -- a 3-time Pro Bowl LB with the Chargers -- says you can't judge everything off drills ... but he ain't gonna question Shaquem's ability to succeed at the next level after all he's been through.