The Kardashians are more rest stop than destination ... so says Tony Rock who says NO ONE should be surprised Tristan Thompson cheated on Khloe.
"Everybody cheats on the Kardashians," Tony told us outside the Laugh Factory ... "You just smash a couple times and you get out!"
Guessing Tony's referring to past K-squad dudes like Lamar Odom and Scott Disick. Kim Kardashian famously told Jennifer Lawrence she was cheated on, too, but didn't call out the cheater by name.
"Who's been loyal to a Kardashain?" Rock added ... "Like for real?"
BONUS: Check out the cameos by Luis Guzman and Russell Peters!
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