Reggie Bush fielded the greatest question of his football career last night -- and by the greatest, we mean the funniest ... because even Reggie couldn't hold back his laughter.
Reggie was in Bev Hills when we brought up his new 4-year, $16 million contract with the Detroit Lions -- and you can't talk Lions running backs without talking about the legendary #20, right?
So ... the question: "Do you think you could possibly be the next Barry Sanders?"
Once you stop laughing ... watch the clip to see Reggie's reaction.
We also asked Reg, and his extremely pregnant gf Lilit Avagyan, about handling the major weather shift -- going from South Beach to Detroit -- 'cause y'know ... it's so cold in the D.