'Sicario' Star Bernardo Saracino Busted for DUI After Medium Speed Chase

One of the drug cartel bad dudes from "Sicario" was on the run from real life cops in L.A. before they chased him down and arrested him for DUI.

Law enforcement sources tell us cops spotted Bernardo Saracino -- drug lord Manuel Diaz in "Sicario" -- around 3:30 AM swerving on an L.A. freeway. Officers lit him up and the chase was on. We're told Saracino refused to pull over for about 8 minutes, leading LAPD cops on a chase that covered 3 freeways ... although never exceeding speed limits.

We're told Saracino -- who's also in Tina Fey's "Whiskey Tango Foxtrot" -- eventually pulled over and surrendered peacefully. Officers booked him for misdemeanor DUI and evading police.

We reached out to Saracino's rep for comment ... so far, no word back.