Michael Douglas' ex-wife wants to make something perfectly clear -- eating out was safe when he was married to her.
Douglas told a British paper over the weekend ... his 2010 throat cancer was "caused by HPV [human papillomavirus], which actually comes about from cunnilingus."
Diandra Douglas -- whose epic divorce from Michael in 2000 was one of the richest marital settlements in history -- tells TMZ she does NOT have HPV ... period.
Guess the ball is in your court now, CZJ.
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