Big Ang: Chemo Not Working ... Trying Cannabis Oil

"Mob Wives" star Big Ang is in dire straits in her fight against stage 4 lung and brain cancer so her family is turning to marijuana as a last resort.

Ang didn't respond to the chemo treatments she started after the New Year, in fact her family says one of the tumors got bigger. Her sister Janine tells us Ang isn't on her deathbed, but her breathing is labored and she's in a lot of pain.

They've decided to try managing her pain with cannabis oil. Some patients believe the alternative treatment can even shrink tumors (that hasn't been scientifically proven) -- but it ain't cheap, going for as much as $60 per gram. The family is raising money via a GoFundMe page.

Ang is too tired to do anything, but Janine is hoping the cannabis oil will at least keep her pain-free.