Adele Sends Her Love to Brangelina

Adele is so shaken by the "end of an era," she dedicated her NYC concert to Angelina Jolie and Brad Pitt -- and it doesn't seem like she was kidding.

Between songs at her Madison Square Garden gig Tuesday night, Adele blurted out ... "Brangelina are broken up!" She admitted the celeb split had been on her mind all day, and this was going to be her moment to work out some feelings. One big giant therapy session ... except her fans were paying.

Check out the clip, if you've seen Adele in concert, you know girl likes to chat. A lot.

Makes ya wonder though ... is Jennifer Aniston an Adele fan?