Jamie Kennedy Goes NUCLEAR on Burping Fan

Jamie Kennedy went crazy on a fan who burped at the wrong time during his standup set.

Jamie was performing in CT Saturday night when a woman burped loudly about 15 minutes into his act. He asked her to apologize, and she refused.

What happens next is sheer comic genius ... well, not comic genius, but pretty epic.

BTW ... we're told the woman and other were kicked out of the show, a lot of people were really drunk and some demanded refunds.