The two had been going back and forth on TMZ Sports earlier this week -- with Floyd calling him an "ant" and Conor daring him to "say that to my face."
But Tuesday night at 1 OAK in NYC, Conor took over the DJ booth, hijacked the mic and called out the boxer for everyone to see.
"Floyd's not ready for this," McGregor said.
"Much respect to Floyd. He's a solid businessman on what he's been able to do ... he's a f**king animal at what he's been able to do. But as far as real fighting ... as far as true pure unarmed combat ... Floyd don't want none of this."
"He wants a boxing match, he doesn't want a fight."
"I want a $100 million cash to fight him under boxing rules ... he's afraid of a real fight."