James Cromwell was back on the frontlines for animal rights this weekend -- taking the fight to Louis Vuitton in the Big Apple ... and showing them they had blood on their hands.
The actor/activist was one of the notable faces among a massive group of protests Saturday who descended upon the Louis V flagship store in SoHo ... where barricades had been set up, and where folks were loudly chanting through megaphones -- complete with signage.
Check out this video we obtained ... you can see that James went past the barricade and was right up on the sidewalk, facing off with what one can presume would be management.
Somewhat dramatically ... he pours some red liquid onto the sidewalk and points it out to Louis Vuitton -- echoing what the protesters behind are shouting. Earlier, he made an impassioned speech in support of veganism -- and laying out what they were there for.