Hayden Panettiere My First Shrooms Trip During 'Scream 4' Was Chaos!!!

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Hayden Panettiere’s memoir isn’t all trauma and family drama -- 'cause she also shared one chaotic Hollywood memory involving 'shrooms, "Scream 4," and David Arquette making a very questionable movie-night choice.

The actress said the whole thing went down back in 2010 while shooting the movie when she, her bestie Allie, and a bunch of twenty-something crew members went glamping at a property rented out by Neve Campbell. That’s where she tried mushrooms for the very first time.

Hayden admitted she had no clue what to expect going into it -- but felt safe doing it around close friends she trusted to keep the weekend stress-free.

Melissa Barrera 'Scream 7' Sucked ... No Way Flick Made That Much $$$ Calls Out Neve Campbell, Other Cast Mates

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Melissa Barrera just slaughtered the "Scream" franchise ... because the actress went scorched earth on the series after she was fired for comments on the Gaza War.

In an interview with Variety ... Melissa didn't hold back when she was asked about the success of the most recent flick ... which was panned by critics -- but made a boatload of money. MB straight up accused Paramount of inflating the box office numbers ... saying there's no way the film did so well.

Important to note ... box office numbers are third-party verified -- so it's impossible for a studio to fudge them.

As you know ... Melissa was booted from "Scream 7" and left her talent agent after friction from her pro-Palestinian messages on social media when the war broke out ... comparing Gaza to a concentration camp.