The man talking the smack is Jesse Holley -- who played WR for the Dallas Cowboys after winning a tryout with the team on Michael Irvin's 2009 reality show "4th and Long."
Holley -- who's 6'3", 215 pounds -- was on 105.3 The Fan in Dallas this morning ... when the gang began questioning if ANYONE will ever defeat the greatest female fighter in UFC history.
That's when Holley suggested ... himself.
Holley says if he had 8 weeks to train ... he's 100% confident he'd squish her like a bug.
FYI -- Cat Zingano was also 100% confident ... and we all know how that went.