Oprah Winfrey is making a full-court press to get Lamar Odom to sit down and unload ... sources connected with both O and Lamar tell TMZ.
We're told no deal has been made, but there have been serious discussions and we're told Lamar is game if the conditions are right.
As for the topics -- drug use, Lamar's troubled marriage to Khloe Kardashian and his future in basketball.
Oprah and Lamar have history ... during her Kardashian special, she spoke with everyone in the family including Lamar. He's been skittish about doing interviews with anyone, but O seems to be an exception.