Blake Griffin's nightmare 2016 continues ... 'cause now one of the biggest -- and hottest (seriously, watch the video) -- models in the world Samantha Hoopes has decided Griffin is no longer bangable.
Hoopes was out enjoying the night life at Super Bowl 50 -- we reiterate, LOOKING SUPER HOT -- when we asked if the hook up offer she made to Blake a while back is still in good standing.
Samantha said she was all about the Clippers stud when we shot her last year ... but that was before he punched out a guy half his size.
Check out the clip -- Hoopes says not only is she off Blake ... she's done with athletes ENTIRELY (yet, she's at the Super Bowl), claiming there's a new segment of rich guys she has her eyes on.
Good news for Blake? Like us, he can still enjoy super hot pictures of Hoopes.
Bad news? He's got an injured right hand.