Drakewasn't only going after Megan Thee Stallion on his new album ... Serena Williams' husband was also name-dropped -- getting called a straight-up "groupie" in a new song.
The OVO rapper released his 16-track joint album, "Her Loss," with 21 Savage on Friday ... and the superstar's hubby, Alexis Ohanian, might not be a fan of a certain track called "Middle of the Ocean."
Here's what he says around the 3:35 mark:
"Sidebar, Serena, your husband a groupie He claim we don't got a problem but No, boo, it is like you comin' for sushi"
Fans went crazy over the bars on social media -- one person called Drake petty and another said Ohanian deserved it, as he's seemingly taken subtle jabs at the rapper in the past.