'Bravo' Star Jeff Lewis Jokingly Calls Kyle Richards 'Lesbian on Ozempic'

Jeff Lewis called Kyle Richards a "lesbian on Ozempic," and while he was certainly joking ... it's a toss-up as to whether the 'Housewives' star herself is laughing.

The famous interior designer -- known for appearing on Bravo's "Flipping Out" -- made the flippant comment on Andy Cohen's show "Watch What Happens Live" ... where they were running a silly segment called 'Jeff, What's Your Issue?' and flashing through faces of people.

Eventually, they landed on Kyle ... and Jeff made the crack, feigning outrage that she didn't tell him she was into women and that she was taking the diabetes weight-loss medication. You could tell it still had an impact though ... 'cause Andy was left blushing on the spot.

Heather McDonald was also on set for this moment, and she ran with the gag ... joking that one of Ozempic's side effects is that it makes people gay. Jeff, who's gay, kept going with it, and the whole thing was dealt with in a light-hearted manner, all told.

Of course ... Jeff's zing comes on the heels of recent speculation Kyle might be dating female country singer Morgan Wade ... this after spending a ton of time with her on the road, and right around the time she separated from her husband, Mauricio Umansky, no less.

Since then, we've learned that's not the case ... and that the reason Kyle's been hanging out with Morgan so much is because of a documentary she's producing about the artist's life.

Still, people have had their opinions about Kyle and Morgan regardless ... something they're well aware of, and which they leaned into in MW's latest music video -- poking fun at all the rumors.

We'll see how Jeff's remarks land with Kyle, who hasn't responded. Not yet.